face bones involvement and relapse in a case of childhood acute leukemia

Face Bones Involvement and Relapse in a Case of Childhood Acute Leukemia

Midface bones are an unusual site for primary presentation and relapse in acute lymphoblastic leukemia. Herein, we describe a case of acute pre B cell lymphoblastic leukemia with leukemic infiltration of maxilla and bone marrow involvement. At the time of relapse, the patient presented again with maxilla involvement and the phenotype changed to biphenotypic lymphoblastic leukemia. Our case sug...

Late relapse in a case of childhood acute lymphoblastic leukemia.

A 14-year-old boy presented first at the age of 5 years in May 1985 with complaints of low backache for 3.5 months, fever for 3 weeks and epistaxis for 10 days. The child was found to have marked pallor, sternal tenderness with no significant lymphadenopathy. No hepatosplenomegaly was found. He had a hemoglobin of 95 g/L; total leukocyte count (TLC) 5000/mm and platelets 60,000/mm with a normal...

Leukemia Cutis in a Child with Acute Lymphoblastic Leukemia at Diagnosis and Relapse

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Evaluation of Relationship between Minimal Residual Disease (MRD) and Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) Using Quantitative Fluorescent PCR

Presenting Clinical and Laboratory Data of Childhood Acute Lymphoblastic Leukemia

Abstract Background Leukemia is the most prevalent childhood cancer and Acute Lymphoblastic Leukemia (ALL) constitutes 75% of all cases. The most frequent presenting symptoms are fever, weight loss and pallor. Early detection of clinical symptoms positively affects timely diagnosis. The objectives of the present study were to assess frequency of presenting symptoms, laboratory data, immune ph...

Survival after relapse in childhood acute lymphoblastic leukemia.

NS One of the most important prognostic factors in childhood ALL is the age of presentation. Patients who present between the ages of 1 and 10 years have the best prognosis, whereas infants tend to have a very poor prognosis. Improvements are being observed within the adolescent age group. The other main prognostic factor is the level of the patient’s white blood count upon presentation. Patien...